There are built-in checks and balances to achieve the most effective and safe treatments for people. The Office for Human Research Protections is tasked with protecting the rights, welfare, and safety of volunteer participants in clinical trials. These guidelines ensure the highest levels of safety, efficacy, and ethical standards are maintained throughout the process. The rules governing clinical studies were put in place by the National Institutes of Health (NIH) and the FDA. From the idea stages to the pill bottle you pick up from your local pharmacy, the research and development of health-related interventions follows strict, well-established guidelines. It takes an average of 10 years for a new drug to enter the market. The FDA approval process for new drugs, also known as the R&D process or pipeline, is rigorous and lengthy. The Research and Development (R&D) Pipeline and Narcolepsy These three new medications offer more choices for those whose narcolepsy symptoms have proven resistant to previously existing treatments. Xywav, which is approved to treat people ages 7 and older with narcolepsy, is expected to become available by the end of 2020. In July 2020, the FDA approved Xywav (calcium, magnesium, potassium, and sodium oxybates) to treat cataplexy or EDS. In October 2020, Wakix was also approved by the FDA for the treatment of cataplexy in adults with narcolepsy. Sunosi was approved by the FDA to treat narcolepsy-related EDS. Wakix is the only drug currently approved to treat narcolepsy that is not a scheduled, controlled substance in the United States. Wakix (pitolisant) and Sunosi (solriamfetol) received approval in 2019. In the past 18 months, the FDA has approved three promising new medications for narcolepsy. Antidepressants like Effexor and Prozac (fluoxetine) have been prescribed for many decades to help treat cataplexy, the defining symptom of type 1 narcolepsy. Stimulants like Adderall (amphetamine/dextroamphetamine) and Ritalin (methylphenidate) are prescribed to combat EDS due to narcolepsy. Several medications are prescribed off-label to treat symptoms of narcolepsy. Xyrem is approved to treat cataplexy in type 1 narcolepsy. Certain medications that block reuptake of serotonin or norepinephrine, like some antidepressants, may reduce cataplexy attacks. Drugs that have wake-promoting or stimulating effects are used to decrease EDS. Food and Drug Administration (FDA) to treat narcolepsy’s key symptoms - EDS, cataplexy, and other sleep disruptions. There are several medications approved by the U.S. Sodium oxybate also reduces sleep-cycle disruptions, including sleep paralysis and sleep-related hallucinations.Xyrem (sodium oxybate) and Effexor (venlafaxine) reduce the frequency and severity of cataplexy attacks.Stimulants and wakefulness-promoting drugs, such as Provigil (modafinil) and Nuvigil (armodafinil), enhance wakefulness.Goals of narcolepsy treatments work in different ways. Narcolepsy is usually treated with a combination of medication and lifestyle changes that promote good sleep hygiene.Ĭurrent narcolepsy treatments are aimed at managing the disruptive symptoms of narcolepsy that impact a person's quality of life. Narcolepsy treatment must be tailored for each person. Current Treatments for Type 1 and Type 2 Narcolepsy More treatments still under research in the development pipeline offer hope for those struggling to manage their narcolepsy symptoms. In the past two years, clinical research has led to several exciting new treatment options for narcolepsy. The benefits of treatments have to be weighed with the risk of side effects, and they don’t always manage to bring symptoms under control. Current narcolepsy treatments are also predominantly controlled substances, due to their risk of abuse. Existing narcolepsy treatments often have significant side effects. In the past, people living with narcolepsy have had limited treatment options. There currently is no cure for narcolepsy, but with medication and behavioral changes, the condition can be managed. Those who experience narcolepsy with EDS but without cataplexy are diagnosed with type 2 narcolepsy. Most people with narcolepsy have type 1 narcolepsy, also known as narcolepsy with cataplexy. Narcolepsy affects approximately 1 in 2,000 people. Narcolepsy is a chronic, neurological disorder characterised by excessive daytime sleepiness (EDS).
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Gorgeous and breathtaking procedurally generated dungeons guarantee a unique experience every time you leave the safety of the Bergson’s home. Find the best prices for The Elder Scrolls V: Skyrim Anniversary Upgrade across 6 different stores, see the full price history, and be the first to find out. Fight through hordes of unfathomable beasts as you explore the darkest depths of this ever-changing mountain. Blasphemous, Catherine: Full Body, and Children of Morta before returning to. Take part in their journey, their struggles, and their victories! Witness the love each has for another, unmatched by even the gods themselves. 95 a month This one comes with thousands of best-seller books, originals. Corruption has seeped into the mountain, spreading and morphing the once peaceful mountain into a violent, monster infested nightmare.Įxperience what it means to be in a family of heroes. The Bergson family has watched over Mount Morta for generations as the guardians of the mystical mountain and the lands surrounding it, but now they face their most dangerous trial as a family. How to teach your child to swim yourself, Throat feels weird after. Dont warn me again for Children of Morta. By clicking View Page, you affirm that you are at least eighteen years old. may not be appropriate for all ages, or may not be appropriate for viewing at work. You get so much more loot and exp just by getting to later stages, so if you do the math (just multiple the cost by ten for profit barrier) the limited money is better spent on other upgrades to get to the later stages. DARK MODE NORMAL THEME About Children of Morta Guess who png, Daftar lagu di my trip my adventure 2018, Best roof colors for resale. Do both players progress their characters in Co-Op :: Children of Morta General Discussions. In hindsight I honestly think the Morv upgrade wasnt necessary at all. On iPhone, iPad, or the Apple TV HD or later, open the App Store and download the Apple Developer app. On the day of the keynote event, open the app to watch the livestream. The Apple TV app is a stock app on the Apple TV, iPhone, and iPad. Some devices may be able to stream the event using a recent version of Chrome or Firefox. Then on the day of the Keynote, visit Apple’s Event page or the official YouTube channel, and you’ll be able to live stream the Keynote event as easily as any Mac user. Visit Apple's official YouTube channel. Apple will add the keynote to the top of its page before WWDC begins.ĭownload the Edge browser by Microsoft for Windows 10 users. Apple should update its Events page with details a few days before WWDC begins. Open Safari and visit Apple’s Event page. On a Mac running macOS version 10.15 or later, open the App Store and download the Apple Developer app. On the day of the keynote event, open the app to watch the livestream. Here are your options for how to watch WWDC 2023: On Mac: This year the conference will include in-person events, but as always, the keynote will be streamed so anyone who wants to can watch it live. The WWDC 2023 keynote will be given at 10:00 a.m. Let's go over everything we know about WWDC 2023. We can expect to hear about iOS 17, iPadOS 17, macOS 14, and watchOS 10 at the keynote, but there are sometimes other surprises in store, and this year it looks like we might be hearing about Apple's new AR/VR headset. Apple may announce a new AR/VR headset, a new Mac Pro, and a 15-inch MacBook Air.Īpple announced that its annual Worldwide Developers Conference will be held June 5–9 this year, with the keynote address being delivered on June 5 at 10:00 a.m.We can expect to get details on iOS 17, iPadOS 17, macOS 14, and watchOS 10, with beta versions of all released shortly after the event.Apple's annual Worldwide Developers Conference will be held June 5–9, with the keynote being delivered June 5 at 10:00 a.m. This event will mark the beginning of the technical autonomy of the North American team. This transfer will also allow him to get the source code of the game, the complete tools but also a hard disk containing various unfinished contents like a draft of the 4th planet: Orlo. With breathable materials, high quality workmanship and best wearing comfort CODE-ZERO expresses it's passion for sailing in colourful collections. This intensive stay will allow him to learn the technical operation of the game and the use of the internal tools. CODE-ZERO is a nautical fashion brand and is developed in collaboration with passionate water sports enthusiasts. Leonis - who can be considered as the American father of Rose Online - is invited to go to Korea to benefit from a week of knowledge transfer with the development team before they move on to another project. (Korea) for any development / correction of the game. Indeed, they had neither the source code of the game, nor the internal development tools. Zero ( Zero) es una identidad enmascarada pública, originalmente creado y asumido por el anterior y exiliado príncipe de Britannia, Lelouch vi Britannia. (USA) had a very limited flexibility regarding the modification of the game. If you don’t have an account yet, click Joinin the site menu.The US branch of Gravity is informed that the original Korean server (kRose) will cease its activity and that the development of the game by the parent company (Korean) will end at the same time. You’re ready to start your wonderful journey of discoveries and adventures that iRosePH offers you! Your client just need to download the latest files from iRosePH servers before you can start your journey. You don’t have to launch it right now, but is highly recommended since your client needs to be updated in order to run the game. Seriously, it’s like you’re actually in the game living out your wildest dreams. Plus, the graphics are out of this world. The product will soon be reviewed by our informers. The irose code zero has something for everyone. The name of the program executable file is iRoseCZ.exe. The most popular version of this product among our users is 1.0. No matter what type of gamer you are first-person shooter, platformer, role-playing, or sports they’ve got you covered. iRose Online - CodeZero Client is developed by iRose Online - CodeZero. Start Rose Online and login to your character. The irose code zero has something for everyone. Then hit OK, and the launcher will now load the Ovr9K.exe client with Noclip, and other features once I make them work. uses Bootstrap, Facebook, Facebook Chat. Open the Rose Online launcher and go to Settings -> Launcher -> Application: and change TRose.exe to Ovr9K.exe. iRose CodeZero O MELHOR LUGAR DE FARM THE BEST FARM PLACE https://. receives about 197 unique visitors per day, and it is ranked 5,887,962 in the world. When the game installation is done, you will see the last step of the Setup Wizard, which will give you an option to launch iRosePH. Content Creator / Disclosure of Rose Online Servers Criador de contedo /Divulgao. In this screen you’ll be able to see every choice you have made during the Setup Wizard, and check if is everything as you want to. CODE-ZERO es una marca de moda náutica y se desarrolla en colaboración con apasionados de los deportes acuáticos. Choose your character from a roster of various classes with different abilities. Explore the vast open-world filled with magic and power as you engage in a variety of quests and challenges. Just click on continue if you want it installed on the default folder, or click on browse button if you want it installed on a different location on your hard drive.Īs additional task for the Wizard, you can select to create a desktop icon, which is pretty good and easy to access the game launcher when you want to play iRosePH. iRose Online: Code Zero is a free-to-play fantasy MMORPG that features a colorful, vivid world with anime-style graphics. Select the drive and folder where you want to have your iRosePH files installed. You’ll see this first step of the Setup Wizard: Once your file is opened, the first thing to do is to select one of available languages of the installer. Then, just open the file “iRosePHOnlineSetup.exe” and the installation guide is ready to begin. After you have downloaded the game client, the first step is to make an exception for iRosePH installation file on your Antivirus software or disable it to let the installation finish without any problems. You can write an entire text in half the time with Phrase Express. There is no clear mention on how long the trial period lasts or if the software is free for personal use. It works as a system tray icon and it is compatible with any software which involves typing. Phrase Express works like an auto-correct tool, but it is more comfortable to use and it features very flexible customization options. This can save you a lot of time when composing writing code, or any other text which contains repetitive phrases. The next time you need to type "if I remember correctly", you can just type "iirc" and the whole phrase will be added automatically. For example, you can type the phrase "if I remember correctly", type "iirc" as the trigger word and select "execute immediately" from the drop menu. Alternatively, you can set Phrase Express to prompt you with a pop-up before anything else by choosing an action from a drop menu. If the program detects that keystroke, it will automatically insert your specified phrase. This can be a word, an abbreviation or anything you want. You just need to type something in a dialog box. The auto-text can be customized beneath the hot key options. When setting a hot key, you can choose to use the Shift, Ctrl, Alt or Win key or all of them by clicking their designated buttons, and the final key from the combination can be selected from a drop menu. Beneath them, you will find a set of easy to use options which will help you configure a hot key or an auto-text. A description and the contents of a phrase can be typed in two separate dialog boxes. Regardless of what you choose from the tree structure, the options on the right side of the window will be the same. They are all organized in a large number of folders and subfolders, according to their categories and it is also possible to create your own folders or phrases. With the aid of a tree structure, on the left side of the settings window, you can access a very wide range of presets, like famous quotes, common abbreviations, salutations and more. Phrase Express offers great flexibility when doing this. With the options found in this settings window you can create pre set words or phrases and set how they will be inserted. The program's interface can be brought up by clicking the Settings option after clicking the system tray icon. As you type, the program will suggest certain words in a pop-up and you can insert a word by clicking one or by hitting the corresponding numpad key. This will not be uncomfortable like a mobile phone's auto-correct function. It will adapt to the words you are typing and it will complete ones automatically. As mentioned before, the program will run as a system tray icon. If you are working in MS Word, a standard notepad or if you are composing an email, Phrase Express will help you with the same efficiency. The software is compatible with anything which involves typing. While going through the installation wizard, you will only have to set a destination path and choose from a few options, such as launching Phrase Express at system startup. The program's setup file is 4 Mb large, so downloading it should not take too long, even on a slower Internet connection. As you type a letter, it will suggest certain words with pop-ups, correct spelling mistakes and more. It will run as a system tray icon and it will work like an auto-correct tool. Using Phrase Express, this type of routine can be automated, saving you valuable time. Official letters, addressed to important people, must contain certain expressions like "Dear sir or madam", "Best regards" and so on. Typing the same words or phrases over and over again can be tiring. But literally nothing comes of it, not even a shark coming close when they get on the boat. they hint at sharks being underwater because the boyfriend is bleeding. There's barely any sense of dread they won't make it, and oh. A random boat, in the middle of nowhere just SHOWS UP because why?! Who knows the movie needed to end I guess! Terrible. Now the finale, think you can't be let down enough? Talk about the most lackluster ending to a disaster/survival movie EVER. The soundtrack has some free royalty music tendencies but overall not the worst thing. One of the worst shots though is when the camera just has the cgi plane centered in the middle and it just looks awful. With that all exterior shots of the plane are CGI and you can notice it. So it rarely felt like they were actually on a plane. So the background was always filled with bloom and the plane never had that realistic turbulence. My main problem was that most of the movie played out on a obvious static plane set with a bunch of green screen. Just so many moments where you think ''why/how?!" and not in a good way. Now what happens when you put two boring actors with no chemistry in a plane together for 1 hour? I guess you just start doing crazy stuff like climbing on the wing and smashing random whisky bottles. They make it such a drawn out and emotional moment (though she can't cry so nothing hits) but ALSO we know almost nothing of their relationship, and suddenly we're supposed to feel this emotional bond? But also when she finally got communication on the radio she mentioned the pilot being dead as one of the last things?! You'd think that would weigh heavier than saying ''I'm the pilot in a happy tone!". And this goes into another scene where she has to push him off the plane to make the plane lighter. But sadly he didn't stick around for long. He brought a bit of levity to the annoyingly serious tone of the movie. Now the one short highlight of this movie was the pilot and actual good actor. just because she doesn't ''like'' to say it?!! I don't physically facepalm during many movies but this made me, the scene was so stupid. From the start of the movie they make the main theme pretty much about her not wanting to say goodbye.not because she had some crazy trauma or anything no. But the writing, oh the writing for the female lead could not be more obnoxious. The lead actress is so dull and is terrible at showing much if any emotion. I expect this kind of acting out of a 80s cliche slasher flick, not something trying to be serious (like really serious). But the first segment feels and is incredibly rushed. The editing does clean up, I mean it's impossible for it not too with this plot. First off something you will instantly notice is the editing, apparently this movie doesn't really care about showing characters moving or traveling, because in the first ten minutes you've been all over the island and introduced to characters we get to know almost nothing about and contribute zero to the story. For such a whimsical and adorable alternate world, it’s a shame Tomodachi Life doesn’t present a more inclusive set of options that would better simulate the world we live in today. Relationships play a special role in Tomodachi Life, but it should be noted that Nintendo takes a very conservative approach to romance in that Miis are only allowed to marry members of the opposite sex. The number of available shops for food, clothing, and other recreational activities expands as more islanders are introduced and more problems get solved - a smart decision that encouraged me to build a community quickly. I never felt pressured to constantly find ways to make money, since plenty of cash gets handed out for solving Mii’s problems. The game offers a dazzling amount of content, humour is perhaps its biggest driving force. It felt at its best when I would randomly check in, see what problems I could solve, and move on. The pace is much lighter than Nintendo’s Animal Crossing series, and Tomodachi Life benefits from it. One day your goals could be as simple as providing an item to relieve a bad stomach ache using the touch-screen, but other days can feel slightly more involved, like offering a suitable location for a Mii to propose to his sweetheart. I thoroughly enjoyed watching them become friends, enter relationships, and even argue with each other without being told to. They seek out sweethearts and best friends, or randomly for new clothing items or skins for their apartments. Once you’ve built up a small community of Miis, the individuals start to develop their own random needs based on their personalities. More importantly, unexpected surprises play a major role in everyday Tomodachi Life. The overall effect of Miis communicating with each other in real English language is welcome and endearing – even though they speak in flat, text-to-speech robotic voices, it adds an extra layer of context and dimension that I’ve never absorbed from listening to Simlish. And they talk! Simple greetings like “Heyo!” or video sign offs like, “You’re watching Mii News…” make the world feel more vibrant and alive. My Miis make brief appearances as news anchors and shopkeepers, pop up at community events, and participate in fun musical performances. That tool empowers me to add whomever I want to my island, be it real-life friends, celebrities, or original creations, and each has one of several personalities and dozens of possible roles to play. They’re both imported from friends via StreetPass and populated with the character creator. Nintendo Miis sit at the center of Tomodachi Life’s friendly drama. Much of what exists in Tomodachi Life is geared towards helping you increase the happiness of your population. At first glance, the touch-screen interface and world seem smaller and simpler than the multi-layered complexity of The Sims, but technical limitations can’t restrain Tomodachi Life’s unique charm or its unabashedly humorous spirit. Instead, a majority of its freeform gameplay lies in observation and responding to the random needs of Miis. Sure, Miis offer to play shallow minigames from time to time, but simple memory or guessing games didn’t keep me entertained at all. Those random events may sound strange, but they also highlight this game’s true purpose: Tomodachi Life is not concerned with the typical game structure like a lengthy campaign of completing objectives and to-do lists. I wish there was a bit more to do in regards to customizing your characters apartments, but you can get by without noticing it.Tomodachi Life With Emulator Free Download Repacklab There is not a tremendous amount of detail but I guess there doesn’t really need to be. The visuals are pretty low poly characters that just jump around or perform menial tasks. I guess, if I were to equate it to anything to give you an idea of what it is about, I would say its like a simple version of Sims 4 Deluxe Edition and Animal Crossing, with visuals a bit closer to Miitopia. You can make the unsuspecting participants sing about literally anything and it can be very, VERY funny. I am telling you, this had me in absolute hysterics for a good while. One of the biggest pulls of this game is the ability to put on a show, get all the Mii’s together, select a genre and then customize all the lyrics of the song that is going to be included. That is all fantastic and there are some definite hijinks to be had, but the real meat of this meal is in the music shows you can put on. You can also buy clothing for the tenants but no one outright tells you what they want, you have to figure it out through trial and error.īesides that, there are a bunch of different mini games available for you which mostly take place in the Mii’s apartments. They do this mostly by themselves but they apparently can’t feed themselves so you need to watch over them for that. 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You can watch the live telecast of today’s match on all TV channels of Star Sports network. All matches schedule updated daily basis. And with that we can wrap up our coverage for this Test match. Star India has the media rights for all the matches played in India till 2025, so you can watch the live streaming of today’s match on Disney+ Hotstar app. Live Cricket Streaming on cricket live tv channels. Follow India vs Australia, 2nd Test, Feb 17, Australia tour of India, 2023 with live. India Squad – Rohit Sharma (Captain), Virat Kohli, Suryakumar Yadav, Ishan Kishan, KL Rahul, Hardik Pandya, Shubman Gill, Ravindra Jadeja, Kuldeep Yadav, Mohammed Shami, Mohammed Siraj, Akshar Patel, Shardul Thakur, Umran Malik, Jaydev Unadkat, Washington Sundar, Yuzvendra Chahal.Īustralia Squad – Steve Smith (captain), David Warner, Cameron Green, Travis Head, Marnus Labuschagne, Sean Abbott, Ashton Agar, Alex Carey, Josh, Mitchell Marsh, Glenn Maxwell, Jhye Richardson, Mitchell Starc, Marcus Stoinis, Adam Zampa. Today Cricket Match 2023 Today Cricket match teams Squad Steven Smith (Captain), David Warner, Travis Head, Marnus Labuschagne, Sean Abbott, Ashton Agar, Alex Carey, Mitchell Marsh, Mitchell Starc, Marcus Stoinis, Adam Zampa. Even Musk tweeted out, saying that users should try it out, but not trust it yet.Rohit Sharma (Captain), Virat Kohli, Suryakumar Yadav, Ishan Kishan, KL Rahul, Hardik Pandya, Shubman Gill, Ravindra Jadeja, Kuldeep Yadav, Mohammed Shami, Mohammed Siraj, Akshar Patel. It will be an opportunity for India to get their XI in order ahead of. However, users are reporting that there are some glaring issues and bugs with the new feature. India vs Australia LIVE Streaming Rohit Sharma’s India takes on hosts Australia in Brisbane on Monday in a warm-up game. How and where to watch the live streaming of the India vs Australia Women’s T20 World Cup 2023 semifinal The India vs Australia Women’s T20 World Cup 2023 semifinal will be streamed live on the Disney+ Hotstar app. Sudan Crisis: UNHRC passes resolution on human rights abuses amid worsening conflictĭuring the opening speech of the session, United Nations High Commissioner for Human Rights Volker Turk accused both forces of violating international humanitarian law.Įlon Musk launches ‘deeply inferior’ encrypted DMs for Twitter Blue users, service riled with issuesĮlon Musk-led Twitter has finally launched encrypted DMs for Twitter Blue subscribers. The India vs Australia Women’s T20 World Cup 2023 will be played at Newlands Cricket Ground in Cape Town. You can also follow the match blog live on. The live streaming of the third Test will also be available on the Disney+ Hotstar website and mobile app. Get Live Scores & Coverage, Ball by Ball Commentary, News, Fantasy Tips. The Border-Gavaskar Trophy fourth Test between India and Australia will be telecast on Star Sports Network. Live Cricket Match Streaming Online & Cricket Highlights & Videos with FanCode. Where can we watch and live stream the Border-Gavaskar Trophy fourth Test between India and Australia in India? India vs Australia - 2023 Latest Highlights Features and Interviews Press Conferences View All GALLERIES View All MEN WOMEN Team sponsor Official broadcaster Title sponsor Official partners CONTACT US 4th Floor, Cricket Centre Wankhede Stadium ‘D’ Road, Churchgate Mumbai- 400020 India. Live Streaming India vs Australia 2021 4th Test Day 4 Updates Ind Vs Aus Live Cricket Score Gabba, Brisbane Telecast On Tv Sony Liv App Jio Tv Sony Six Sony Ten, India vs Australia 2021 4th Test. Toss on Day 1 will take place at 9 AM IST. The Border-Gavaskar Trophy fourth Test between India and Australia will begin at 9:30 AM IST. What time will the Border-Gavaskar Trophy fourth Test between India and Australia begin? The Border-Gavaskar Trophy fourth Test between India and Australia will be played from 9 March and can go up to 13 March. When will the Border-Gavaskar Trophy fourth Test between India and Australia be played? How do I watch the live streaming of the India vs Australia 1st ODI match The. The Border-Gavaskar Trophy fourth Test between India and Australia will be played at the Narendra Modi Stadium in Ahmedabad. The India vs Australia 1st ODI match will be televised on Star Sports Network channels in India. Where will the Border-Gavaskar Trophy fourth Test between India and Australia be played? Here’s all you need to know about when and where to watch the fourth Test between India and Australia: Steve Smith will lead Australia for a second time this series, and it remains to be seen if they would make a change from their match-winning third Test. Survival curves were estimated using the Kaplan–Meier method and compared by the log rank test. Combined with the MELD-XI score, the final model was adjusted, and the predictive ability of the model was evaluated. Cox regression and lasso regression were used to screen variables and build a prognostic model. The primary clinical outcome was all-cause mortality within 3 years. Methods: This is a retrospective cohort study of patients with chronic heart failure who were initially hospitalized in the Second Affiliated Hospital of Chongqing Medical University from February 2017 to December 2017. The aim of this study was to determine the long-term prognostic relationship of MELD-XI score in patients with chronic heart failure. Objectives: The relationship between the MELD-XI score, a modified version of the MELD score, and the long-term prognosis of hospitalized patients with chronic heart failure is unclear. 8Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.7Department of Cardiology, The First Affiliated Hospital of University of Science and Technology of China, Hefei, China.6Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.5Department of General Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.4Clinical Research Center for Respiratory Disease (tumor) in Anhui Province, Bengbu, China.3Anhui Province Key Laboratory of Clinical and Preclinical Research in Respiratory Disease, Bengbu, China.2Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital, Bengbu Medical College, Bengbu, China.1Department of Geriatrics, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, China.Zebin Lin 1 †, Xia Liu 2,3,4 †, Li Xiao 5, Yin Li 6, Chenlu Qi 5, Siqi Song 5, Yiping Zhao 7 and Lili Zou 8 * |